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How Stem Cells Could Help Treat Diabetes Traditional strategies for the treatment of diabetes have not produced a cure so far, but they’ve helped with management of the condition. Yet, studies based on stem cells indicate that these have the potential to help manage as well as cure diabetes. In this article, we look at why stem cells therapy for diabetes are a viable approach. The urgency to develop alternative therapies for diabetes originates from the lack of efficacy of current therapies. For instance, isolated islet cells transplantation may be able to treat diabetes. The only issue is that this therapy is mostly not viable. To begin with, the number of donors is significantly lower than the required islet cells transplantation. In addition, the treatment cannot be meaningful unless there’s enough amounts of great quality islet cells.
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Another complication is that the immune system may reject the transplants unless drugs are used to suppress it, which can lead to more vulnerability to diseases. Yet, even upon suppression, the immune system will ultimately defeat the transplanted islet cells, and that will call for further transplantation.
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Pluripotent Stem Cells Therapy The creation of beta cells from pluripotent stem cells and transplanting these into a patient can fix diabetes. Pluripotent stem cells can transform into any required body cell function, and if they can be made to fully function as beta cells, treatment of diabetes becomes effective. Producing beta cells from pluripotent stem cells in large quantities can resolve the problem of human donor scarcity. According to research, the produced cells have been seen to respond to glucose in the same manner as naturally produced beta cells. Hope in the Creation of Beta Cells from Other Cells Some studies suggest the possibility of encouraging cells that are already present in the pancreas of a diabetic patient to produce new beta cells that in turn can help treat the condition. There may be no evidence of stem cells existence in the pancreas, but beta cell progenitors are present, and these may be activated to offer an effective remedy. There are also efforts to reprogram other mature pancreas cells, or cells from other parts of the body, such as the skin or liver, to make beta cells in the lab in large quantities. Work is ongoing to produce an effective cushion for the transplanted beta cells against damage by the immune system of the patient. If the immune reaction can be reduced, a diabetic patient will not have to use drugs that expose them to additional health complications. If you suffer from any form of diabetes, there’s hope for a lasting remedy in stem cells therapy for diabetes. The right diabetes remedy won’t negatively affect your overall health.